Some medicines may interact with lidocaine/prilocaine gel. Tell your health care provider if you are taking any other medicines, especially any of the following:
Antiarrhythmics (eg, mexiletine, tocainide), beta-blockers (eg, propranolol), cimetidine, or other medicines containing lidocaine or prilocaine because the risk of side effects or toxic effects, including heart or nerve problems, may be increased
Acetaminophen, acetanilide, aniline dyes (eg, p-phenylenediamine), benzocaine, chloroquine, dapsone, naphthalene, nitrates (eg, nitroglycerin, isosorbide), nitrites (eg, sodium nitrite), nitrofurantoin, nitroprusside, pamaquine, para-aminosalicylic acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine, or sulfonamides (eg, sulfamethoxazole) because the risk of side effects, including blood problems, may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if lidocaine/prilocaine periodontal gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.